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However, DIO mice switched from an obesity-promoting WD to an LD (regardless of treatment status) displayed several genera and phyla differences compared to obese and lean controls

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This is most relevant when vitamin B12 deficiency is being corrected and broader B-vitamin support is clinically appropriate, where symptoms include a combination of fatigue, neurological features, and stress, or where rapid repletion and functional support are desired

Studies have shown that blood MOTS-c levels in young people are 11% and 21% higher than those in middle- and old-aged people, respectively (30)