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This shift not only allows for rapid production of energy but also for maintenance of NADH/NAD + redox ratio, which is required for metabolic processes, such as aerobic glycolysis, the TCA cycle, OXPHOS, FAO, serine biosynthesis and antioxidant defense

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B-Ras proteins function in both Ral and NF-B signaling pathways (Oeckinghaus et al, 2014), and attribution of the observed in vivo phenotype of B-Rasdeficient mice to deregulation of Ral signaling was circumstantial

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doi: 10.1080/19490976.2017.1290758 93

Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells