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Description

Intestinal epithelial cells primarily degrade Trp via the kynurenine pathway, which is essential for regulating colonic inflammation and colorectal cancer [114]

Following successful model induction, the Uricase and RBC@SeMSN@Uri groups received intravenous injections of 10 mg/kg Uricase or RBC@SeMSN@Uri at 0 h, coinciding with the cessation of fructose feeding