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Key Takeaways Peptides are prescription compounds in the United States and must be prescribed and supervised by a licensed medical provider, not dispensed by a spa or sold through a membership portal without labs

Wen et al., 2025), cardiomyopathies, pulmonary hypertension (Mocumbi et al., 2024), ischemia reperfusion injury (Sharp et al., 2014) and metabolic syndromes (obesity, hyperglycemia, and a range of liver problems) (Muraresku et al., 2018

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However, individuals with active acne, rosacea, or highly sensitive skin should consult a dermatologist before opting for microdermabrasion, as it may exacerbate these conditions

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doi: 10.1016/j.cub.2019.10.016 106 LiuJ.FuC.LiG.KhanM