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A promising priority lies in developing dual-target nanotherapeutics capable of concurrently suppressing ferroptosis drivers (e.g., ACSL4) and amplifying immunoregulatory pathways (e.g., Treg activation), thereby enabling synergistic correction of both redox and immune dysfunction

When outside the body, they are deprived of the natural detoxification system

Transient overexpression of the P450 enzyme via Agrobacterium tumefaciens infiltration, implemented in E

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The primary inoculum was prepared by transferring 1 mL of the stock culture to 30 mL of LB medium in a 250 mL flask and culturing at 37 C for 6 h