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The central mechanism of epileptic seizure is the epileptogenesis process which occurs due to an imbalance between inhibitory and excitatory neurotransmitters (Li et al

doi: 10.1016/j.nbd.2023.106200 28 Huntemer-SilveiraA.PatilN.BricknerM

22-23] Based on these findings, the CAFC disagreed that a skilled person would have believed that the process described in the 779 Patent would be a promising method of eliminating ABUKs