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The GNCsiRNA (100 nM siRNA equivalent) exhibited greater inhibition on NGF mRNA expression, with 75% downregulation of NGF mRNA expression compared to the nontreated control (Fig

In tumors, persistent ROS elevation increases GSH synthesis and shifts the redox balance, creating a biochemical environment that selectively activates disulfide/diselenide linkers and metal-based GSH-depleting nanoplatforms

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R-2HG exhibits anti-tumor activity by targeting FTO/m(6)A/MYC/CEBPA signaling

Reinke, S