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W.BrownJ

10.1016/j.ibmb.2014.03.012

Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie

In contrast, it significantly decreased the populations of T helper type 1 (Th1) and type 17 (Th17) cells (65), which produce proinflammatory cytokines and mediate inflammation in the CNS mainly in patients with MS (66) as well as in those with EAE (6771)

In this context, ferroptosis has garnered increasing attention as a promising target for early diagnostic strategies, given that iron accumulation in the SN is a characteristic feature of PD