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All duplicate articles identified during the search were excluded

Statistical analysis All data were expressed as mean standard deviation

doi: 10.1038/cdd.2017.65 61 ShubinaMTummersBBoydDFZhangTYinCGautamAet al

Kammona O, Kiparissides C

Our results suggest that a crucial neurodegeneration pathway in glaucoma may involve the effect of extracellular zinc on the activity of the neurotropic factor PEDF and consequently its receptor PEDF-R, which may thus represent relevant targets for neuroprotective therapy