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Who Should NOT Use BPC-157 Pregnant or breastfeeding women insufficient safety data Active or recent cancer theoretical angiogenesis concern Uncontrolled bleeding disorders Known peptide allergy Uncontrolled severe cardiovascular disease without specialist clearance Drug Interactions Formal interaction data is limited

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Recently we reported that the AT4 receptor antagonist Norleual- AngIV (Nle-YI--(CH2-NH2)-HPF) inhibited HGF binding to c-Met and in turn HGF-dependent signaling, proliferation, invasion, and scattering [78]