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Metformin (Glumetza, Fortamet, others)

B12 oral supplements are also readily available but these take longer to work and there is no guarantee that the body will absorb them effectively due to the digestion process

Participants treated with the drug experienced a 35.3% reduction of ocular discomfort, 59.1% reduction of total corneal fluorescein staining and increased tear production as compared to those who received a placebo [11]

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Broad preclinical activity can be scientifically interesting without automatically translating into safe, predictable, clinically meaningful human outcomes