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The hepatotoxicity of PZA is dose-dependent, especially at doses above 40 mg/kg, and correlates with its hepatic metabolism, suggesting a direct toxic effect rather than a hypersensitive or immune-mediated mechanism

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It has been noted that women smokers in the USA at least are more likely than men smokers to be light daily smokers and so the greater risk to women of light smoking will impact disproportionately on study outcomes [35]

Teeth Smoking staining happens when the chemicals in cigarettes damage the enamel and deposit tar and other residues in the teeth

"'Mouse' is a syllable," the philosopher wrote in a letter to his friend Lucilius, according to a translation of his works by Richard Mott Gummere, a former Latin professor at Haverford College in Pennsylvania