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In addition, the presence of CKD increased cardiovascular risk and mortality in patients with diabetes

328 Covalent conjugation of targeting ligands, and/or polymeric materials such as PEG chains, carboxymethyl cellulose, dextran could distinctively facilitate the transport of IONPs across the BBB

Additional isoprenoid derivatives, including dolichol, heme A, and ubiquinone (coenzyme Q), contribute to protein glycosylation, mitochondrial respiration, and redox balance 46

EC-77 Scheme No

As key regulators of ion and metabolite transport between neurons and other glial cells, astrocytes serve as essential hubs in the brains network

Moreover, a higher absorption rate leads to a lower dosage of active constituents to exert a biological effect, as well as polar phytoconstituents (105)