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From a clinical perspective, the lack of large-scale human trials means it cannot yet be considered an established therapy

Compounds like Tesamorelin, AOD9604, and Semaglutide are investigated for their impact on fat metabolism, glucose regulation, and appetite signaling

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These studies indicate the potential of utilizing the de novo pathway, a less extensively studied pathway, as a therapeutic strategy for metabolic diseases Barth syndrome is a rare disease caused by mutations in the tafazzin gene encoding for cardiolipin (CL), a phospholipid specific for the mitochondria 303

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