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PMC 4586882

Curr Med Chem 29:37743789

We recently showed that mitochondria-associated ER membranes (MAM) are key sites for LD biogenesis and growth, identifying the existence of tripartite mitochondria-ER-LD junctions (MAM-LD contacts), that act as metabolic hubs for lipid transfer and storage (Monteiro-Cardoso and Giordano 2024

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Consequently, emerging therapeutic strategies that directly target the core pathophysiological mechanisms of IBD have been developed, offering a new avenue to overcome the limitations of existing regimens and to improve long-term outcomes