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This method bypasses first-pass liver metabolism, allowing lower doses for equivalent effects

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Chari A, Minnema MC, Berdeja JG, et al

These blood clots can lead to serious health complications, including deep vein thrombosis (DVT), pulmonary embolism (PE), and stroke

However, weight loss from GLP-1 therapy can improve insulin sensitivity and reduce blood sugar levels, which may require adjustments to diabetes medications such as insulin or sulfonylureas