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The Medicines and Healthcare products Regulatory Agency has not approved it for any clinical use, and it cannot lawfully be marketed for human consumption, sold as a supplement, or prescribed on the NHS

On the other hand, POI is defined by disruption of the HPO axis, which can lead to amenorrhea or oligomenorrhea, low levels of estradiol, and increased gonadotropin levels 6,7

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It functions as a multi-pathway signal peptide affecting fibroblast activity, copper trafficking, antioxidant signaling, and broad gene expression

neither does my functional PCP and I was just found to have this gene disorder