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Bispecific nanobody activity measured by macrophage phagocytosis Previous studies have demonstrated that PD-L1 antibodies can significantly enhance the proliferation and activation of macrophages in vivo, leading to a proinflammatory phenotype 29,30

doi: 10.1016/j.bbadis.2020.165747 128 DixonSJPatelDNWelschMSkoutaRLeeEDHayanoMet al

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As well, natural compounds can increase the level of Microtubule-associated protein 1A/1B-light chain 3 (LC3-II), a marker of autophagy, that is decreased in PD which leads to the accumulation of -Syn aggregates (Wang et al

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By contrast, in cancer cells, de novo fatty-acid synthesis is commonly elevated and the supply of cellular fatty acid is highly dependent on the de novo synthesis