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As a result, the production of immunosuppressive adenosine in cancer cells was reduced, ultimately preventing macrophages from acquiring an M2 immunosuppressive phenotype

2.3 Measurement of urine GPX4 by feline commercial GPX4 ELISA kit Urine GPX4 levels in the cats were measured using a species-specific commercial ELISA kit (MBS093863, MyBioSource, USA) by following the manufacturers instructions

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In 2014, the FDA instructed AstraZeneca to add new safety information about nephritis to the labels of all prescription PPIs, including Nexium, as part of a petition filed by the Public Citizen