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2022 July;26(13):378396

Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain

p-JNK induces the opening of the mitochondrial permeability transition (MPT) pore, increasing the mitochondrial permeability and the pore transition ( Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor encoded by the NFE2L2 gene that NAPQI can indirectly activate