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Notably, localized mechanical rupture, membrane perforation, and pressure-induced deformation collectively undermine the structural integrity of microbial cells

aureus metabolism, leading to the discovery of KL1, a host-directed compound that sensitizes persisters to antibiotic killing

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Genomics 113 (3), 889899

The quality of evidence is categorized based upon an assessment of study methodology, including risk of bias, evidence of publication bias, heterogeneity among studies, and precision of the estimate of eradication rates