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Ergothioneine is not produced by humans or plants and is only made by fungi

Lifespan extension was driven by oxidative stress, as supplementation with the antioxidant N-acetylcysteine (NAC) abolished this effect

doi: 10.1080/15563650902752376.

For model training, we performed hyperparameter tuning of the L1 regularization parameter, , with five-fold cross validation using the GridSearchCV function from scikit-learn