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Erastin-induced ferroptosis via the Xc-mediated ROS/P38-MAPK pathway feedback loop presents novel strategies for comprehensive treatment of GC [97]

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Neurotoxicity in dopamine and 5-hydroxytryptamine terminal fields: a regional analysis in nigrostriatal and mesolimbic projections

Using a combination of RNAseq and metabolomics analysis of mouse liver samples taken 3 h and 6 h after introduction of dietary MR, in conjunction with in vitro analysis of methionine-restricted HepG2 cells, our data suggest that the rapid initial decrease in hepatic methionine decreases ternary complex formation, slows overall translation, and induces an ISR that is modulated by mTOR, Erk1/2, and ATF4

(2006) detected S-nitrosylated PDI aggregates in the brains of patients with AD and PD, suggesting that NO-mediated impairment of ER proteostasis contributes to neurodegeneration

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