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As you get older, the systems that rely on NAD+ (like energy production, cognitive function, skin repair, immune health, and inflammation regulation) start to slow down, and declining NAD+ levels appear to be a key driver behind that slowdown

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On top of that, any NAD+ that your cells do have left gets used up faster in response to stress, illness, or environmental damage

Reviews typically cant control for confounders (diet changes, exercise, stimulant intake, sleep, stress, or other supplements), and negative experiences are often underreported

Reassuring yourself the effects are temporary as your body adjusts