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Prausnitz and Kstner phenomenon: the P-K reaction

Ser/gly pathway metabolites are required for RT recovery in NSCLC To validate the observations in the plasma of patients with NSCLC and confirm our hypothesis of augmented ser/gly pathway dependency, we performed 13 C 6 -glucose tracing and metabolomics analysis in a panel of 5 NSCLC cell lines, i.e., NCI-H1299, NCI-H125, NCI-H1975, Calu-6 and NCI-H520 to identify the RT related metabolic changes

Meanwhile, PCEF@Fe employs a cooperative strategy: it chelates copper to weaken cellular defenses while simultaneously releasing iron to initiate ferroptosis, illustrating a novel approach for the coordinated targeting of multiple cell death pathways (Hua et al., 2025)

Article ID 794643, 10 pages

Switzerland: Springer (2022)

Hippocampus 14 , 153162 (2004)