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Immediately after the surgery, the TBI rat received LC (1.5 mM in drinking water) or Exendin-4 (15 g/kg, once daily, ip, Auspep, VIC, Australia) for 14 days

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The disadvantage to this type of injection is that injected medication may stay in the back side of the spine away from the intervertebral disc

The pyruvate can then be burned in the Krebs cycle if pyruvate dehydrogenase is active, exported from the cell if not or converted to lactate by lactate dehydrogenase

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