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Since adipose tissue is responsive to endotoxins, bacterial translocation may provide a mechanism whereby the gut microbiome can modulate the adipose metabolome (for review, Kruis et al., 2014 23 ) and consequently exacerbate obesity and its related comorbidities

Anwendung Das Arzneimittel wird in der Regel intramuskulr verabreicht (in einen Muskel gespritzt)

Glucagon Receptors are the third and most novel target

2.1 Literature search A systematic search of the PubMed, EMBASE, Cochrane Library, Web of Science, and CNKI databases for relevant observational studies published until 15 March, 2022, was undertaken independently by two reviewers (Zhao and Li)

One compound reduces energy intake, the other increases energy expenditure at the mitochondrial level