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Cancer controls the various hallmarks by governing the energy metabolism alterations, genome instabilities, and inflammation by employing the normal cells to recruit and sustain the microenvironment required for the propagation of cancer

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125 The expression of the antioxidant enzymes in islet cells is low, leading to a greater tendency for them to be affected by oxidative stress

Additionally, glutamate-cysteine ligase (GCL) was upregulated, whereas other enzymes in the GSH synthesis pathway were not affected by ethanol (Fig