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Pyruvate dehydrogenase complex inactivation, caused by phosphorylation from overactive pyruvate dehydrogenase kinases, is a process in cancer development

However, this study still has certain limitations

Gastrointest Endosc 2006;63:570-80

Step 2 Consider additional markers if borderline Your physician may also test methylmalonic acid (MMA) and homocysteine both rise when B12 is functionally deficient at the cellular level, even when serum B12 appears near-normal