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4.2 Potential targets and drugs for HDT in MTB with diabetes mellitus T2DM mice exhibit increased body weight, blood glucose levels, glucose tolerance, insulin resistance, and increased susceptibility to MTB infection

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These future directions and ongoing developments are expected to accelerate the translation of AC from bench to bedside, ultimately expanding its therapeutic utility across diverse disease contexts

Heart A decrease in cardiac NAD + levels is causally linked to metabolic abnormalities and mitochondrial dysfunction, which contribute to the pathologies of heart failure [148,149,150]

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Hereditary haemorrhagic telangiectasia: current views on genetics and mechanisms of disease