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Section 60, lot 673, grave 2

Gene regulation by small interfering RNA (siRNA) The RNAi pathway can be activated by the entry of a transgene that provides long dsRNA or a virus

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As a proof of concept, we tested this signature in previously published bulk RNA-sequencing (RNA-seq) data from in vitro OSKM reprogramming 40 , and found it was significantly enriched in iPS cells as compared to the mouse embryonic fibroblasts (MEFs) from which the iPS cells were derived (Extended Data Fig