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It can be common to have significant pain for the first 6 weeks following surgery and through the night

Rohatgi PR, Swisher SG , Correa AM, Wu TT, Liao Z, Komaki R, Walsh GL, Vaporciyan AA, Rice DC, Bresalier RS, Roth JA, Ajani JA

Dennery PA

Sanyal AJ, Chalasani N, Kowdley KV, et al

Under the conditions of exposure to low-intensity light at night and circadian disruption that only suppresses nocturnal melatonin production, both the Warburg effect and the uptake of LA and its metabolism to 13-HODE in breast cancer xenografts become completely arrhythmic and operate at a constitutively high level throughout the entire day (all 24-hrs).[ref][ref] Let me point out here that melatonin production decreases with age and cancer rates increase with age There is a lot of epidemiological evidence tying cancer rates especially breast and prostate cancer to exposure to light at night, which decreases peak melatonin production

And then the cycle starts again