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This route could be experimentally measured by the assessment of TEER

Conflicts of interest Kong D is an Editorial Board member of the Journal Cancer Drug Resistance , while the other authors have declared that they have no conflicts of interest

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Additionally, it brightens and nurtures the skin, helping to maintain an even skin tone

This implies that upstream modulators like KEAP1 may be more important than direct Nrf2 modulation as the primary mechanism 104

Phase I metabolism involves enzymes such as cytochrome P450 (CYP) enzymes, flavin-containing monooxygenases (FMO), alcohol dehydrogenases, and esterases, among others