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Interestingly, the dysfunction of the stress-regulating neuroendocrine system in elderly people along with the ageing-dependent oxidative stress are equivalent to those in humans exposed to chronic stress (99, 100)

The Modern Stress Epidemic and Nutrient Depletion Stress comes in many forms psychological pressures from work deadlines, emotional challenges, and physical strain from sedentary lifestyles and poor nutrition

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Ann Oncol 29(6):1445-1453, 2018