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Amnesia was induced via intracerebroventricular (icv) administration of scopolamine at a dose of 70 nmol in 2 l artificial cerebrospinal fluid, with control animals receiving either aCSF or distilled water

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In opposite, other studies showed that a high-fat diet significantly elevated the zinc level in plasma in rats [83]

The disease was first noticed in the United States in the early 1900s, around the time processed foods were introduced into the American diet

A hundred years ago, the author of this theory, characterized by the conversion of glucose into lactate, pointed out that this effect was the result of a mitochondrial defect, thus generating a universal metabolic alteration