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1C, E), identifying typical intracellular inclusions similar to previously reported inclusion patterns in the AD brain 12,13

After a high-fat diet, male and female rats showed, respectively, increased Fe and S level in the organ

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We nevertheless included the 2YF/2YA mutants in functional assays of G6PD, not to demonstrate a role as a phosphorylation-defective surrogates but to show that G6PD catalytic activity is essential for the Lac-GSTP1-G6PD axis to regulate the pentose phosphate pathway