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[DOI] [PubMed] [Google Scholar] 161.Mellott T.J., Huleatt O.M., Shade B.N., Pender S.M., Liu Y.B., Slack B.E., Blusztajn J.K

PKC activation disrupts normal metabolism, leading to ATPase phosphorylation and metabolic disorders, including changes in VEGF and vasoconstriction, which affect pain perception

doi: 10.1016/j.heliyon.2024.e31895 377 SabuMCSmithaKRamadasanK

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While ZIP1 controls the influx of zinc into postsynaptic cells, ZIP3 manages the re-uptake of zinc into dentate granule cells

This approach provides both the systemic gene expression modulation from injections and concentrated local delivery from topical application