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Next, we used a targeted LC-MS metabolomics assay to confirm these trends in one additional sensitive cell line (U87) and one additional resistant cell line (A172)

ATP (adenosine triphosphate) acts as a co-substrate for both enzymes (Figures 2, 3)

[7] [9] These contraindications are based on known metabolic pathways, clinical case reports, and established pharmacological principles, and are supported by clinical guidelines and expert consensus

doi: 10.3389/fphar.2019.00204 187 PerryV

As a manufacturer of food supplements, we are not permitted due to legal requirements to provide information on the physiological effects of red yeast rice extract