(Cham: Springer International Publishing), 301322
Indeed, the clinical literature exhibits heterogeneity in design, dosing, duration, and outcome measures, frequent reliance on parent reported scales without uniform blinding, and underpowered samples that hinder strong inference and guideline development ( in vivo studies explicitly exclude female animals to avoid potential confounding effects related to hormonal fluctuations
Reisman SA, Ferguson DA, Lee CI, Proksch JW
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