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The chapter begins with Sections 6.2 and 6.3 summarizing the modes of oil exposure to organisms (including humans) and the mechanisms of oil toxicity by which oil may harm organisms, recognizing similarities and differences across taxonomic groups

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6.3.1 CYP450-derived HETE in RCC Kidney epithelial cells typically express high levels of CYP4504A and CYP4F family enzymes and robustly produce 20-HETE, and it is likely that RCC can produce 20-HETE (Alexanian et al., 2009)