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J Crit Care 48:314320 Dubin A, Eguillor JFC, Ferrara G, Buscetti MG, Canales HS, Lattanzio B, Gatti L, Gutierrez FJ, Edul VSK (2023) Lack of change in the respiratory quotient during oxygen supply dependence in endotoxemic shock: a subanalysis of an experimental controlled study

Its shelf life in solution, combined with its extended half-life, makes it more practical for research uses compared to native IGF-1, which needs more frequent use and careful handling

It is also used to treat pernicious anemia, vitamin B 12 deficiency (due to low intake from food or inability to absorb due to genetic or other factors), thyrotoxicosis, hemorrhage, malignancy, liver disease and kidney disease

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These can include: Mild irritation, redness, or tingling: These are typically transient and may subside as the skin adjusts