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Beneficial effects of UA, including antioxidant activity, are believed to be mediated through the activation of the Nrf2/Kelch-like ECH-associated protein 1 (Keap1) signaling pathway [45]

But, no one knows whether the effects of acetyl-L-carnitine are from the chemical itself, from the L-carnitine it can make, or from some other chemical made along the way

2003 Aug;94( 2):123-9 Iketani T, Kiriike N, Murray, Stein B, Nagao K, Nagata T, Minamikawa N, Shidao A, Fukuhara H

0012, (2014/10/29) A method for producing a therapeutic agent and the agent thus produced

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The major role of OCTN2 in carnitine absorption and tissue distribution is demonstrated by the existence of a human disease caused by inborn defects of the OCTN2 gene, namely PCD (Magoulas and El-Hattab, 2012)