glutathione for bipolar Future Pharmacotherapy Disorders: Emerging Trends and Personalized Approaches Glutathione-conjugating enzymes, glutathione S-transferase (GST)

The samples were read using a 2104 Envision plate reader with excitation at 340 nm and emission at 490 and 520 nm

Lower concentrations (e.g., 1mg/mL using 5mL water) improve measurement accuracy but require larger injection volumes and may reduce stability due to increased surface area exposure to oxygen

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However, it is not yet clear what metabolic determinants are critical for therapeutic resistance and evasion of immune surveillance

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The animal study was reviewed and approved by Animal welfare and ethics committee from Peking Union Medical College Hospital