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Higher concentrations are achieved by using mixtures (for example 15% DMSO in combination with 15% ethylene glycol) which reduces the amount and toxicity of the individual cryoprotectants 10

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Tocotrienol-rich fraction ameliorates antioxidant defense mechanisms and improves replicative senescence-associated oxidative stress in human myoblasts

Activated JNK phosphorylates numerous cytoplasmic substrates, including cytoskeletal proteins and mitochondrial proteins like Bcl-2 and Bcl-xl, in addition to controlling a few transcription factors, including c-Jun, c-Fos, ATF-2, AP-1, p53, and Elk

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