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MTHFR Pathways should not be used with a sulfur sensitivity, as it contains a sulfur-based amino acid

10.1016/s0021-9258(18)95928-4 4 AckersG

Perioperative implications were evaluated with emphasis on orthopaedic surgical risk domains relevant to total joint arthroplasty (TJA), including wound complications, hematoma formation, immune modulation, infection susceptibility, heterotopic ossification, and implant fixation considerations

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