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Although the size increased, the size of the functionalized nanoparticles was still in a range that was deemed suitable for topical application, indicating that the HA functionalization did not affect the desired delivery essentials of the nanoparticles on the skin

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Expert Opin Pharmacother 13(6):895905 Srinivasan V, Pandi-Perumal SR, Trahkt I, Spence DW, Poeggeler B, Hardeland R, Cardinali DP (2009) Melatonin and melatonergic drugs on sleep: possible mechanisms of action

While numerous supplements may relieve constipation, a few may also cause or worsen it

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Treatment of both Mock and MST6-I cells with secretomes from different adipocyte types did not affect the proliferation rates of either cell line [Figure 5A]