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Chiang, A

PSP is caused by damage to nerve cells in areas of the brain that control thinking and body movements

MH was validated to prevent neuronal death and synaptic damage, improve motor function, and reduce anhedonic and depressive-like behaviors of PD mice

For instance, PDK4 overexpression has been reported to promote tumorigenesis in contexts where cancer cells rely on mitochondrial oxidative metabolism, such as in prostate cancer [150]

Cancer treatments such as chemotherapy and radiation can impact the nervous system and cause unusual pain signals

This molecular remodeling of the BBB facilitates the transmigration of peripheral immune cells, including T lymphocytes and monocytes/macrophages, across the vascular barrier and their subsequent infiltration into the CNS parenchyma (53, 54)