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Sun et al

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Alabdali A, Al-Ayadhi L, El-Ansary A (2014) A key role for an impaired detoxification mechanism in the etiology and severity of autism spectrum disorders

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Oxidative stress affects numerous molecular pathways, including inhibition of the cystine/glutamate antiporter system, decreased expression of GPX4, disruption of iron homeostasis and lipid peroxidation, which is a major driver of ferroptosis activation (54)

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doi: 10.1016/j.jchromb.2016.02.009

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Nutrients 13:2878

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