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Nanaomycin A, the first DNMT3B-selective compound, provides a valuable biochemical tool and benchmark for future studies

Lv Q-K, Tao K-X, Wang X-B, Yao X-Y, Pang M-Z, Liu J-Y, et al

74 MillerS

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ALS-related mutations reduce the ability of SOD1 to fold, bind necessary metal cofactors and predispose it to disulphide reduction, which in turn prevents its normal dimerization