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Islam et al., 2024)

Heres whats actually happening at the molecular level

The interaction between vitamin B12 and Apolipoprotein E (APOE) significantly influences cognitive function in older adults, with APOE carriers showing a stronger positive association between vitamin B12 levels and cognitive performance compared to noncarriers [61]

Aside from these TMA-generating processes from dietary trimethylamines, some gut microbes like have also been found to have another pathway that converts TMAO to TMA via the activity of a torA-like gene product which acts as a reductase [78, 79]